As per a new paper, breathing in dirty air could result in the transfer of hazardous particles from the lungs to the brain, which could cause brain diseases and neurological problems. Numerous inhaled fine particles were found to use a straightforward blood circulation pathway, which was discovered by a global team of researchers from the University of Birmingham in the United Kingdom and establishments in China. Evidence suggests that once they reach the brain, the particles remain there more than in other major metabolic organs.
Posted in the journal PNAS on Monday, the new study revealed a way by which harmful particulate compounds may enter the brain from cerebrospinal fluids obtained from patients with brain problems. Professor Iseult Lynch of the University of Birmingham, one of the study’s co-authors, says we don’t know enough about the brain-damaging consequences of airborne small particles.
The discovery offers new insight into the relationship between the inhalation of particles and their subsequent movement throughout the body. Air pollution and the negative effects on the brain are now linked, according to recent studies suggesting that up to eight times as many small particles may flow by circulation from the lungs than simply pass through the nose.
It is important to understand that air pollution is a concoction of numerous toxins, but particulates, particularly ambient tiny particles including PM2.5, are the most harmful. Biological barriers and sentinel immune cells can’t stop ultrafine particles, according to these researchers.
Scientists say that recent evidence shows a substantial connection involving polluted air and neurological alterations similar to Alzheimer’s disease, as well as cognitive impairments in older adults and even children. A team of researchers discovered that breathed particles can infiltrate the bloodstream after passing the air-blood barrier, ultimately hitting the brain and causing harm to the brain as well as the blood barrier and adjacent tissues.
They found that the particles remained in the brain for a longer period of time than in any other organ and were difficult to remove. New research shows that particle pollution poses a threat to the central nervous system, according to the study. More examination into the dynamics as to how inhaled ambient small particles enter the brain is required, according to the experts.
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